Southern blotting and DNA fingerprinting

DNA fingerprint analysis is based on the “Southern” hybridization technique. In this method: DNA fingerprinting, also termed DNA profile analysis is based on the use of the “Southern” hybridization technique to analyze polymorphic regions of human DNA. Polymorphisms are explained in more detail in problem 5. The experimental steps used in a forensics laboratory for …

Interresting questions about chromosomal abnormalities

1- Assume that a meiotic-nondisjunction event causes trisomy 8 in a newborn. If two of the three copies of chromosome 8 are absolutely identical, at what point during meiosis did the nondisjunction event take place? 2- If all the nondisjunction events leading to Turner syndrome were paternal in origin, what trisomic condition might be expected …